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Zocor 20mg 50 tabs, Simvastatine

Zocor 20mg 50 tabs, Simvastatine
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Zocor 20mg 50 tabs, Simvastatine


SIMLO® is anHMG-CoAreductaseinhibitor (statin) indicated as an adjunctivetherapy todiet to:

  • Reduce therisk of totalmortality byreducing CHDdeaths andreduce therisk of non-fatalmyocardialinfarction,stroke, and the need forrevascularizationprocedures inpatients at highrisk ofcoronaryevents.

  • Reduce elevated total-C, LDL-C, Apo B, TG andincrease HDL-C inpatients withprimaryhyperlipidemia (heterozygousfamilial and nonfamilial) and mixed dyslipidemia.


    • Hypersensitivity to anycomponent of thismedication.

    • Activeliverdisease, which may include unexplained persistentelevations inhepatic transaminaselevels.

    • Women who arepregnant or may becomepregnant.

    • Nursingmothers.



      As a general proposition, before starting treatment with ZOCOR, the patient should follow a standard diet to lower cholesterol, which must be continued throughout the treatment.

      Patients with coronary heart disease should start treatment with 20 mg of ZOCOR in a single dose at night, and if necessary, adjust the dose at intervals of four weeks, reaching maximum of 80 mg, supplied by the night in one shot. LDL below 75 mg / dl (1.94 mmol / l) or total cholesterol below 140 mg / dl (3.6 mmol / l) recommend lowering the dose of simvastatin.

      In patients with hyperlipidemia, the recommended starting dose is 10 mg daily in one dose at night.

      In homozygous familial hypercholesterolemia, the recommended dose is 40 mg administered at night, or 80 mg daily in three divided doses of 20, 20 and 40 mg, simvastatin must be used in these patients as an adjunct to other treatments reducing lipids.

      ZOCOR drugs may be associated with bile acid sequestrants. Patients who are treated concomitantly with cyclosporine, fibrates or nicotinic acid, should receive high doses of simvastatin, 10 mg daily.

      Although ZOCOR not renally excreted significantly and there is no need to adjust your dosage in patients with moderate renal impairment, in those with significant renal insufficiency with creatinine clearance below 30 ml / minute, doses above 10 mg daily are not recommended.


  • Name of the medication:Simlo
  • Comparative brand name medication:Zocor
  • Active substance:Simvastatina
  • Presentation: Tab
  • Concentration:10 mg
  • Time release: No
  • Bottle with 50 tab
  • Made in: Mexico



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