Canesten Vaginal Cream 20 gr, Clotrimazole
THIS IS THE BRAND MEDICATION
THERAPEUTIC INDICATIONS: OVULES Canesten ® V is a broad-spectrum antifungal vulvovaginal infections by fungi and yeasts (especially Candida albicans), Candida glabrata, Trichomonas vaginalis, yeast colpitis and / or trichomonas. In the case of Canesten ® V Cream can be used also in patients with Candida balanitis. In vaginitis occurring with dry preferably recommended the administration of eggs or cream, and to relieve itching, burning or irritation to external genitalia (vulva) associated with vaginal infection.
Pharmacokinetics in Humans: Under appropriate test conditions, the minimum inhibitory concentrations (MIC) for dermatophytes, yeasts and molds are at levels of 0.0642 to 4 mg / l. The type of action is primarily fungistatic, although dermatophytes and Candida spp are fungicidal effects from higher concentrations of 10-20 mg / l. Canesten ®, in vitro, also shows antibacterial properties against Gram-positive cocci and corynebacteria with MIC values â€‹â€‹between 0.5-10 mg / l and 100 mg / l tricomonicida effect.
Canesten ® investigations with radioactively labeled with 14C, administered as 100 mg vaginal tablet gave a vaginal absorption between 3 and 10% of the administered dose. The concentration of active principle not modified in the plasma, after vaginal administration of the tablet 100 or 500 mg and vaginal cream to 2%, was always found below the limit check. Clotrimazole is metabolized in the liver and a small portion is excreted via the bile. Due to the poor absorption of Canesten vaginal ® in any form should not be considered a systemic effect.
The concentrations of clotrimazole in the vagina remain up to 3 days after the application.
Contraindications: Unless a possible hypersensitivity to clotrimazole, there are no contraindications.
PRECAUTIONS: It may present development of irritation and / or sensitization, so that in these cases treatment should be discontinued and implement corrective actions.
Use in Pregnancy and Lactation Canesten ® V in all its forms can be applied during pregnancy and lactation. In pregnancy should preferably be used for vaginal tablets, either 100 or 500 mg, without the applicator. The experimental and clinical tests give no indication that the application of Canesten ® V during pregnancy can be expected harmful effects to mother or infant. However, during the first trimester of pregnancy, like all drugs, the use of Canesten ® V is under the responsibility of the treating physician.
ADVERSE REACTIONS: light can reach us to present demonstrations of local irritation.
DRUG INTERACTIONS AND OTHER GENDER: There are no reported drug interactions. Canesten ® V in any of its presentations Ia can reduce effectiveness and safety of latex products (such as condoms and diaphragms) and spermicidal vaginal, however, this effect is temporary and occurs only during treatment.
CHANGES IN RESULTS OF LABORATORY TESTS: None reported to date.
PRECAUTIONS IN RELATION TO EFFECTS OF CARCINOGENESIS, MUTAGENESIS, Impairment of Fertility: There are no reports to date.
DOSAGE AND ADMINISTRATION: Vaginal.
A vaginal suppository daily for three consecutive days, preferably at bedtime.
Instructions for administration: For all dosage forms of Canesten ® Vaginal see specific instructions for each presentation annex on the package.
The pharmaceutical forms of Canesten ® Vaginal be introduced as deeply as possible into the vagina, preferably with the patient in the supine position with legs slightly bent. It is recommended that your application preferably at night, at bedtime.
To ensure effectiveness we recommend:
• Carry out the treatment during the days without menstruation.
• In cases of balanitis spouse, that it shall apply Canesten ® Cream for 2 weeks.
• Carry out the treatment without intercourse for sexually active.
REPRESENTATIONS AND MANAGEMENT Overdosage: No cases on record of overdose or accidental ingestion.
Canesten ® comes in box with 3 ovules of 200 mg and instructive.
RECOMMENDED STORAGE: Store at room temperature to no more than 30 ° C and dry.
LEGENDS OF PROTECTION:
Keep out of reach of children. Exclusively for the medical literature.
- Drug Name: Canesten V
- Brand comparison: Canesten V
- Active ingredient: Clotrimazole
- Presentation: Ovules
- Concentration: 200 mg
- Response time: No
- Lab: Bayer, S. A. de CV
- Egg Box with 3 ovules
- Manufactured in: Argentina
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