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XL-3 VR 24 Tabs, Acetaminophen

XL-3 VR 24 Tabs, Acetaminophen
Model:650240017100
Current Reviews:0
Price:$4.52

XL-3 VR 24 Tabs, Acetaminophen

Chlorphenamine AMANTADINE PARACETAMOL ( ACETAMINOPHEN ) )

Cold products without antimicrobials ( R5A )

genomma_XL -3 VR_tabletas.png
DOSAGE AND ADMINISTRATION
STORAGE
ALTERATIONS OF LABORATORY TESTS
Contraindications
SIDE EFFECTS:
Pregnancy and Lactation
Pharmacokinetics
Dosage form
INDICATIONS:
Interactions
LEGENDS OF PROTECTION
PRECAUTIONS
WARNINGS
PRESENTATION
OVERDOSE

DOSAGE AND ADMINISTRATION: Oral .
Adults and children over 12 years , take 2 tablets every 12 hours for 6 days.

RECOMMENDED STORAGE : Store at room temperature to no more than 30 ° C and dry temperature.

CHANGES IN RESULTS OF LABORATORY TESTS : They have reported increases in serum creatinine determinations , alkaline phosphatase , bilirubin , uric acid, BUN and CPK .

Hypersensitivity to the components of the formula. Should not be administered to patients with functional damage in liver and kidney , and those taking monoamine oxidase inhibitor drugs (MAO ) or who have been treated with them in the previous two weeks, patients with decompensated diabetes mellitus , glaucoma , prostatic hypertrophy , hypertension, history of bronchial asthma. Not to be used in people who have a history of neuropsychiatric disorders. Not to be taken concurrently with nervous system depressant drugs nor alcohol , nor should be administered to children under 12 years .

ADVERSE REACTIONS : In some cases you may have hypertension, sedation is evident particularly drowsiness , reduced alertness and ability to concentrate .

To a lesser extent it may have dry mouth, blurred vision , dizziness and gastrointestinal disorders such as anorexia, vomiting , epigastric difficulties. Other effects include decreased libido, nausea, headache and restlessness , sometimes insomnia and nervousness. After administered for prolonged periods have been presented liver and kidney damage , hypertension , tachycardia, and palpitations. Eventually leucopenia and neutropenia.

RESTRICTIONS OF USE DURING PREGNANCY AND BREAST-FEEDING : Do not use during pregnancy and lactation.
Pharmacokinetics: amantadine hydrochloride is a synthetic molecule ( L - amantadine ) that is rapidly absorbed through the gastrointestinal tract and is capable of preventing influenza type A. Its action starts about 30 minutes after administration and persists for several hours , so the elimination is impaired in patients with renal insufficiency and in people over 65. After oral administration of 200 mg amantadine maximum plasma concentration of 0.25 and 0.5 ug / ml , same as that reached 2 to 3 hours, its half life is between 10 and 15 hours. The volume of distribution is 3 to 8 L / kg and its bioavailability is between 85 and 90 % .

Amantadine cross the blood brain barrier and the placenta, and is widely distributed in the tissues, especially lungs , heart and brain. Binds 65 % bound to plasma proteins and hardly metabolized . 90% of the administered dose is eliminated amantadine practically exclusively with urine by glomerular filtration and tubular secretion without any metabolism . The elimination in subjects with normal renal function is 11 to 15 hours, but is increased significantly in patients with renal failure, while debugging is 1.5 times higher in men than in women. In the elderly, the removal is prolonged from 24 to 30 hours, while acidification of the urine increases renal excretion .

Paracetamol is rapidly absorbed from the gastrointestinal tract and is evenly distributed into tissues and body fluids . The plasma concentration peaks at 30 to 60 minutes after oral administration. It is metabolized in the liver and excreted in the urine mainly as glucuronide and sulfate conjugates , less than 5% is excreted unchanged . The elimination half life is 2 to 4 hours. Binding to plasma proteins is variable, from 20% to 50 % may be bound at the concentrations encountered during acute intoxication. Acetaminophen produces analgesia and antipyretic . It is useful in the treatment of mild to moderate intensity. Paracetamol exerts antipyretic to act on the thermoregulatory center causing heat loss by peripheral vasodilation and sweating action.

Chlorpheniramine maleate an H1 antagonist is slowly absorbed from the gastrointestinal tract , reaching peak plasma concentrations within 2 to 3 hours, while the maximum therapeutic effect at 5 hours , having a duration of effect of 4 to 6 hours. It has an elimination half-life of 21-27 hours is widely distributed in tissues and body fluids by binding to plasma proteins by 72 %. It is metabolized first in the gastric mucosa presenting a first pass metabolism in the liver and is widely distributed in the body, including the central nervous system. Chlorphenamine excreted through urine and urine pH dependent flow rate . Its absorption is faster in fasting . Using chlorpheniramine orally in adults is 3-4 mg every 4 to 6 hours (maximum 24 mg daily) , while in children under 1 year is not recommended.

Based on the absorption characteristics of the components of the formula XL ® VR -3 , the analgesic effect as determined by the antihistamine chlorpheniramine paracetamol and has an onset at approximately 30 minutes , allowing an immediate symptomatic patients discomfort while amantadine inhibits replication of influenza virus .

Dosage form :

Each tablet contains:

Chlorpheniramine maleate 3 mg

Amantadine hydrochloride 50 mg

Paracetamol 375 mg

Excipient c.b.p. 1 tablet.
INDICATIONS: Influenza antiviral action , antihistamine, decongestant , analgesic and antipyretic indicated as an adjunct against seasonal influenza. XL-3 ® VR acts against the influenza virus causing the group A, including its subtypes and is an assistant to relieve some discomfort of the common cold such as body aches , congestion, runny nose , sneezing , pain and fever .
VR -3 ® XL helps reduce flu symptoms , reduce complications and reduces disease .
 
DRUG INTERACTIONS : Should not be taken concurrently with nervous system depressant drugs , alcohol , anticholinergics , antiepileptics, metoclopramide and propantheline . Acetaminophen may enhance the effect of oral anticoagulants. Should not be given concomitantly with monoamine oxidase ( MAO). Should not be administered with other medications containing chlorpheniramine , since power amantadine side effects.

Name of product: XL-3 VR
Comparable patent medicine: XL-3 VRActive ingredient: AMANTADINA / Acetaminophen /Chlorpheniramine
Presentation: Chewable Tablets
Concentration: 50mg/375mg/3mg
Extended-release tablets: No
Laboratory Selder, Inc. de CV
Box of 24 Pills
Made in: Mexico


   
   
   
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